Atypical Familial Amyotrophic Lateral Sclerosis with Slowly Progressing Lower Extremities-predominant Late-onset Muscular Weakness and Atrophy

OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by the progressive loss of the upper and lower motor neurons that progresses to paralysis of almost all skeletal muscles of the extremities, bulbar, and respiratory system. Although most ALS case...

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Veröffentlicht in:Intern Med
Hauptverfasser: Togawa, Jumpei, Ohi, Takekazu, Yuan, Jun-Hui, Takashima, Hiroshi, Furuya, Hirokazu, Takechi, Shinji, Fujitake, Junko, Hayashi, Saki, Ishiura, Hiroyuki, Naruse, Hiroya, Mitsui, Jun, Tsuji, Shoji
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Japanese Society of Internal Medicine 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663526/
https://ncbi.nlm.nih.gov/pubmed/31257275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.2222-18
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