Uterine Gα(q/11) signaling, in a progesterone-dependent manner, critically regulates the acquisition of uterine receptivity in the female mouse

A nonreceptive uterus is a major cause of embryo implantation failure. This study examined the importance of the Gα(q/11)-coupled class of GPCRs as regulators of uterine receptivity. Mice were created lacking uterine Gα(q) and Gα(11); as a result, signaling by all uterine Gα(q/11)-coupled receptors...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: de Oliveira, Vanessa, Schaefer, Jennifer, Calder, Michele, Lydon, John P., DeMayo, Francesco J., Bhattacharya, Moshmi, Radovick, Sally, Babwah, Andy V.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662978/
https://ncbi.nlm.nih.gov/pubmed/31091422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900026R
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