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The promise of selecting individuals from the extremes of exposure in the analysis of gene-physical activity interactions

BACKGROUND: Dichotomization using the lower quartile as cutoff is commonly used for harmonizing heterogeneous physical activity (PA) measures across studies. However, this may create misclassification and hinder discovery of new loci. OBJECTIVES: This study aimed to evaluate the performance of selec...

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Detalhes bibliográficos
Publicado no:Hum Hered
Main Authors: Osazuwa-Peters, Oyomoare, Schwander, Karen, Waken, RJ, de las Fuentes, Lisa, Kilpeläinen, Tuomas O., Loos, Ruth J. F., Racette, Susan B., Sung, Yun Ju, Rao, D. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662918/
https://ncbi.nlm.nih.gov/pubmed/31167214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000499711
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