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Bidirectional optogenetic modulation of prefrontal-hippocampal connectivity in pain-related working memory deficits

Dysfunction of the prefrontal-hippocampal circuit has been identified as a leading cause to pain-related working-memory (WM) deficits. However, the underlying mechanisms remain poorly determined. To address this issue, we implanted multichannel arrays of electrodes in the prelimbic cortex (PL-mPFC),...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cardoso-Cruz, Helder, Paiva, Pedro, Monteiro, Clara, Galhardo, Vasco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662802/
https://ncbi.nlm.nih.gov/pubmed/31358862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47555-0
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