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Meiosis I progression in spermatogenesis requires a type of testis-specific 20S core proteasome

Spermatogenesis is tightly regulated by ubiquitination and proteasomal degradation, especially during spermiogenesis, in which histones are replaced by protamine. However, the functions of proteasomal activity in meiosis I and II remain elusive. Here, we show that PSMA8-associated proteasomes are es...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Zhang, Qianting, Ji, Shu-Yan, Busayavalasa, Kiran, Shao, Jingchen, Yu, Chao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662770/
https://ncbi.nlm.nih.gov/pubmed/31358751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11346-y
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