Generation of human induced pluripotent stem cells from individuals with a homozygous CCR5Δ32 mutation

Chemokine receptor 5 (CCR5) is the primary coreceptor for HIV entry into macrophages. Individuals with a homozygous deletion of 32 bp in the CCR5 gene (CCR5Δ32) are highly resistant to HIV infection (Samson et al., 1996). Allogeneic stem cell transplantation from a healthy donor with the homozygous...

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Publicat a:Stem Cell Res
Autors principals: Chen, Guibin, Jin, Hui, Yu, Zhen, Liu, Yangtengyu, Li, Zhongwen, Navarengom, Keron, Schwartzbeck, Robin, Dmitrieva, Natalia, Cudrici, Cornelia, Ferrante, Elisa A., Biesecker, Leslie G., Yang, Dan, Boehm, Manfred
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662727/
https://ncbi.nlm.nih.gov/pubmed/31234109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2019.101481
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