Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis

Accumulating evidence illustrates a fundamental role for mitochondria in lung alveolar type 2 epithelial cell (AEC2) dysfunction in the pathogenesis of idiopathic pulmonary fibrosis. However, the role of mitochondrial fusion in AEC2 function and lung fibrosis development remains unknown. Here we rep...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Chung, Kuei-Pin, Hsu, Chia-Lang, Fan, Li-Chao, Huang, Ziling, Bhatia, Divya, Chen, Yi-Jung, Hisata, Shu, Cho, Soo Jung, Nakahira, Kiichi, Imamura, Mitsuru, Choi, Mary E., Yu, Chong-Jen, Cloonan, Suzanne M., Choi, Augustine M. K.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662701/
https://ncbi.nlm.nih.gov/pubmed/31358769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11327-1
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