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Efficient biosynthesis of 2-keto-D-gluconic acid by fed-batch culture of metabolically engineered Gluconobacter japonicus
2-keto-d-gluconic acid (2-KGA) is a key precursor for synthesising vitamin C and isovitamin C. However, phage contamination is as constant problem in industrial production of 2-KGA using Pseudomonas fluorescens. Gluconobacter holds promise for producing 2-KGA due to impressive resistance to hyperton...
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| Udgivet i: | Synth Syst Biotechnol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
KeAi Publishing
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6661466/ https://ncbi.nlm.nih.gov/pubmed/31384676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2019.07.001 |
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