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Peroxisome proliferator-activated receptor α attenuates high-cholesterol diet-induced toxicity and pro-thrombotic effects in mice

Peroxisome proliferator-activated receptor α (PPARα) is involved in the regulation of fatty acid and cholesterol metabolism. A high-cholesterol (HC) diet increases the risk of developing cardiovascular diseases (CVD); however, it is unclear whether the toxic effects of cholesterol involve changes in...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Lu, Yu, Harada, Makoto, Kamijo, Yuji, Nakajima, Takero, Tanaka, Naoki, Sugiyama, Eiko, Kyogashima, Mamoru, Gonzalez, Frank J., Aoyama, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661123/
https://ncbi.nlm.nih.gov/pubmed/30341732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2335-4
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