Intravitreal delivery of VEGF-A(165)-loaded PLGA microparticles reduces retinal vaso-obliteration in an in vivo mouse model of retinopathy of prematurity

PURPOSE: Retinopathy of prematurity (ROP) is a condition of abnormal retinal vascularization with reduced levels of vascular endothelial growth factor (VEGF) causing vaso-obliteration (Phase I), followed abnormal neovascularization from increased VEGF (Phase II). We hypothesized that intravitreal pr...

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Udgivet i:Curr Eye Res
Main Authors: Mezu-Ndubuisi, Olachi J., Wang, Yuyuan, Schoephoerster, Jamee, Falero-Perez, Juliana, Zaitoun, Ismail S., Sheibani, Nader, Gong, Shaoqin
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661072/
https://ncbi.nlm.nih.gov/pubmed/30383455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02713683.2018.1542736
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