Tailoring the lipid composition of nanoparticles modulates their cellular uptake and affects the viability of triple negative breast cancer cells

Lipid nanoparticles are used widely as anticancer drug and gene delivery systems. Internalizing into the target cell is a prerequisite for the proper activity of many nanoparticulate drugs. We show here, that the lipid composition of a nanoparticle affects its ability to internalize into triple-nega...

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Veröffentlicht in:J Control Release
Hauptverfasser: Abumanhal-Masarweh, Hanan, da Silva, Dana, Poley, Maria, Zinger, Assaf, Goldman, Evgenya, Krinsky, Nitzan, Kleiner, Ron, Shenbach, Gal, Schroeder, Josh E., Shklover, Jeny, Shainsky-Roitman, Janna, Schroeder, Avi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660975/
https://ncbi.nlm.nih.gov/pubmed/31238049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.06.025
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