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Family-Based Quantitative Trait Meta-Analysis Implicates Rare Noncoding Variants in DENND1A in Polycystic Ovary Syndrome

CONTEXT: Polycystic ovary syndrome (PCOS) is among the most common endocrine disorders of premenopausal women, affecting 5% to15% of this population depending on the diagnostic criteria applied. It is characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology. PCOS i...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Dapas, Matthew, Sisk, Ryan, Legro, Richard S, Urbanek, Margrit, Dunaif, Andrea, Hayes, M Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660913/
https://ncbi.nlm.nih.gov/pubmed/31038695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-02496
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