Trpc5 deficiency causes hypoprolactinemia and altered function of oscillatory dopamine neurons in the arcuate nucleus

Dopamine neurons of the hypothalamic arcuate nucleus (ARC) tonically inhibit the release of the protein hormone prolactin from lactotropic cells in the anterior pituitary gland and thus play a central role in prolactin homeostasis of the body. Prolactin, in turn, orchestrates numerous important biol...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Blum, Thomas, Moreno-Pérez, Ana, Pyrski, Martina, Bufe, Bernd, Arifovic, Anela, Weissgerber, Petra, Freichel, Marc, Zufall, Frank, Leinders-Zufall, Trese
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660783/
https://ncbi.nlm.nih.gov/pubmed/31285329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905705116
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