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α-synuclein−lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinson's disease patients

The progressive accumulation, aggregation, and spread of α-synuclein (αSN) are common hallmarks of Parkinson’s disease (PD) pathology. Moreover, numerous proteins interact with αSN species, influencing its toxicity in the brain. In the present study, we extended analyses of αSN-interacting proteins...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Paslawski, Wojciech, Zareba-Paslawska, Justyna, Zhang, Xiaoqun, Hölzl, Katharina, Wadensten, Henrik, Shariatgorji, Mohammadreza, Janelidze, Shorena, Hansson, Oskar, Forsgren, Lars, Andrén, Per E., Svenningsson, Per
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660770/
https://ncbi.nlm.nih.gov/pubmed/31270237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821409116
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