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Antigen structure affects cellular routing through DC-SIGN

Dendritic cell (DC) lectins mediate the recognition, uptake, and processing of antigens, but they can also be coopted by pathogens for infection. These distinct activities depend upon the routing of antigens within the cell. Antigens directed to endosomal compartments are degraded, and the peptides...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jarvis, Cassie M., Zwick, Daniel B., Grim, Joseph C., Alam, Mohammad Murshid, Prost, Lynne R., Gardiner, Jaye C., Park, Soyeong, Zimdars, Laraine L., Sherer, Nathan M., Kiessling, Laura L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660738/
https://ncbi.nlm.nih.gov/pubmed/31270240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820165116
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