Mineralocorticoid Antagonism and Vascular Function in Early Autosomal Dominant Polycystic Kidney Disease: A Randomized Controlled Trial

RATIONALE & OBJECTIVE: Vascular dysfunction, characterized by impaired vascular endothelial function and increased large-elastic artery stiffness, is evident early in autosomal dominant polycystic kidney disease (ADPKD) and is an important predictor of cardiovascular events and mortality. Aldost...

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Detalhes bibliográficos
Publicado no:Am J Kidney Dis
Main Authors: Nowak, Kristen L, Gitomer, Berenice, Farmer-Bailey, Heather, Wang, Wei, Malaczewski, Mikaela, Klawitter, Jelena, You, Zhiying, George, Diana, Patel, Nayana, Jovanovich, Anna, Chonchol, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660387/
https://ncbi.nlm.nih.gov/pubmed/30803706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.ajkd.2018.12.037
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