Preclinical insights into cholangiopathies: disease modeling and emerging therapeutic targets

INTRODUCTION: The common predominant clinical features of cholangiopathies such as primary sclerosing cholangitis (PSC), primary biliary cholangitis (PBC), and biliary atresia (BA) are biliary damage/senescence and liver fibrosis. Curative therapies are lacking, and liver transplantation is only opt...

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Pubblicato in:Expert Opin Ther Targets
Autori principali: Sato, Keisaku, Glaser, Shannon, Kennedy, Lindsey, Liangpunsakul, Suthat, Meng, Fanyin, Francis, Heather, Alpini, Gianfranco
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660346/
https://ncbi.nlm.nih.gov/pubmed/30990740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2019.1608950
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