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Fungal Kinases With a Sweet Tooth: Pleiotropic Roles of Their Phosphorylated Inositol Sugar Products in the Pathogenicity of Cryptococcus neoformans Present Novel Drug Targeting Opportunities

Invasive fungal pathogens cause more than 300 million serious human infections and 1.6 million deaths per year. A clearer understanding of the mechanisms by which these fungi cause disease is needed to identify novel targets for urgently needed therapies. Kinases are key components of the signaling...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Main Authors: Lev, Sophie, Li, Cecilia, Desmarini, Desmarini, Sorrell, Tania C., Saiardi, Adolfo, Djordjevic, Julianne T.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660261/
https://ncbi.nlm.nih.gov/pubmed/31380293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00248
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