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Computational estimation of ms-sec atomistic folding times

Despite the development of massively parallel computing hardware including inexpensive graphics processing units (GPUs), it has remained infeasible to simulate the folding of atomistic proteins at room temperature using conventional molecular dynamics (MD) beyond the μs scale. Here we report the fol...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Adhikari, Upendra, Mostofian, Barmak, Copperman, Jeremy, Subramanian, Sundar Raman, Petersen, Andrew A., Zuckerman, Daniel M.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660137/
https://ncbi.nlm.nih.gov/pubmed/30892023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b10735
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