Metabolic engineering of Rhodococcus ruber Chol-4: A cell factory for testosterone production

Rhodococcus ruber Chol-4 is a potent steroid degrader that has a great potential as a biotechnological tool. As proof of concept, this work presents testosterone production from 4-androstene-3,17-dione by tailoring innate catabolic enzymes of the steroid catabolism inside the strain. A R. ruber quad...

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Pubblicato in:PLoS One
Autori principali: Guevara, Govinda, Olortegui Flores, Yamileth, Fernández de las Heras, Laura, Perera, Julián, Navarro Llorens, Juana María
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660089/
https://ncbi.nlm.nih.gov/pubmed/31348804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220492
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