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Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo.

Desmoplakin (Dsp) is a unique and critical desmosomal protein, that is integral to epidermal development. However, it is unclear whether this protein is required specifically for epidermal morphogenesis. Using morpholinos or Crispr/Cas9 mutagenesis we decreased the function of Dsp in frog embryos to...

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Détails bibliographiques
Publié dans:Dev Biol
Auteurs principaux: Bharathan, Navaneetha Krishnan, Dickinson, Amanda J.G.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659752/
https://ncbi.nlm.nih.gov/pubmed/30935896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.03.010
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