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Novel high-coverage targeted metabolomics method (SWATHtoMRM) for exploring follicular fluid metabolome alterations in women with recurrent spontaneous abortion undergoing in vitro fertilization

The complexity of follicular fluid metabolome presents a significant challenge for qualitative and quantitative metabolite profiling, and for discovering the comprehensive biomarkers. In order to address this challenge, a novel SWATHtoMRM metabolomics method was used for providing broad coverage and...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Song, Jingyan, Wang, Xiaoming, Guo, Ying, Yang, Yi, Xu, Kaiyue, Wang, Tianqi, Sa, Yuanhong, Yuan, Lihua, Jiang, Huaying, Guo, Jiayin, Sun, Zhengao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659694/
https://ncbi.nlm.nih.gov/pubmed/31350457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47370-7
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