The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis

BACKGROUND: Evidence linking breast size to breast cancer risk has been inconsistent, and its interpretation is often hampered by confounding factors such as body mass index (BMI). Here, we used linkage disequilibrium score regression and two-sample Mendelian randomization (MR) to examine the geneti...

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Detalhes bibliográficos
Publicado no:Int J Epidemiol
Main Authors: Ooi, Brandon Nick Sern, Loh, Huiwen, Ho, Peh Joo, Milne, Roger L, Giles, Graham, Gao, Chi, Kraft, Peter, John, Esther M, Swerdlow, Anthony, Brenner, Hermann, Wu, Anna H, Haiman, Christopher, Evans, D Gareth, Zheng, Wei, Fasching, Peter A, Castelao, Jose Esteban, Kwong, Ava, Shen, Xia, Czene, Kamila, Hall, Per, Dunning, Alison, Easton, Douglas, Hartman, Mikael, Li, Jingmei
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Mendelian Randomization
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659372/
https://ncbi.nlm.nih.gov/pubmed/31243447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyz124
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