The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis

BACKGROUND: Evidence linking breast size to breast cancer risk has been inconsistent, and its interpretation is often hampered by confounding factors such as body mass index (BMI). Here, we used linkage disequilibrium score regression and two-sample Mendelian randomization (MR) to examine the geneti...

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Dettagli Bibliografici
Pubblicato in:Int J Epidemiol
Autori principali: Ooi, Brandon Nick Sern, Loh, Huiwen, Ho, Peh Joo, Milne, Roger L, Giles, Graham, Gao, Chi, Kraft, Peter, John, Esther M, Swerdlow, Anthony, Brenner, Hermann, Wu, Anna H, Haiman, Christopher, Evans, D Gareth, Zheng, Wei, Fasching, Peter A, Castelao, Jose Esteban, Kwong, Ava, Shen, Xia, Czene, Kamila, Hall, Per, Dunning, Alison, Easton, Douglas, Hartman, Mikael, Li, Jingmei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Mendelian Randomization
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659372/
https://ncbi.nlm.nih.gov/pubmed/31243447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyz124
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