Mendelian randomization analysis of C-reactive protein on colorectal cancer risk

BACKGROUND: Chronic inflammation is a risk factor for colorectal cancer (CRC). Circulating C-reactive protein (CRP) is also moderately associated with CRC risk. However, observational studies are susceptible to unmeasured confounding or reverse causality. Using genetic risk variants as instrumental...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Epidemiol
Prif Awduron: Wang, Xiaoliang, Dai, James Y, Albanes, Demetrius, Arndt, Volker, Berndt, Sonja I, Bézieau, Stéphane, Brenner, Hermann, Buchanan, Daniel D, Butterbach, Katja, Caan, Bette, Casey, Graham, Campbell, Peter T, Chan, Andrew T, Chen, Zhengyi, Chang-Claude, Jenny, Cotterchio, Michelle, Easton, Douglas F, Giles, Graham G, Giovannucci, Edward, Grady, William M, Hoffmeister, Michael, Hopper, John L, Hsu, Li, Jenkins, Mark A, Joshi, Amit D, Lampe, Johanna W, Larsson, Susanna C, Lejbkowicz, Flavio, Li, Li, Lindblom, Annika, Le Marchand, Loic, Martin, Vicente, Milne, Roger L, Moreno, Victor, Newcomb, Polly A, Offitt, Kenneth, Ogino, Shuji, Pharoah, Paul D P, Pinchev, Mila, Potter, John D, Rennert, Hedy S, Rennert, Gad, Saliba, Walid, Schafmayer, Clemens, Schoen, Robert E, Schrotz-King, Petra, Slattery, Martha L, Song, Mingyang, Stegmaier, Christa, Weinstein, Stephanie J, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Gruber, Stephen B, Peters, Ulrike, White, Emily
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Mendelian Randomization
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659358/
https://ncbi.nlm.nih.gov/pubmed/30476131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyy244
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