Mendelian randomization analysis of C-reactive protein on colorectal cancer risk

BACKGROUND: Chronic inflammation is a risk factor for colorectal cancer (CRC). Circulating C-reactive protein (CRP) is also moderately associated with CRC risk. However, observational studies are susceptible to unmeasured confounding or reverse causality. Using genetic risk variants as instrumental...

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Bibliografiske detaljer
Udgivet i:Int J Epidemiol
Main Authors: Wang, Xiaoliang, Dai, James Y, Albanes, Demetrius, Arndt, Volker, Berndt, Sonja I, Bézieau, Stéphane, Brenner, Hermann, Buchanan, Daniel D, Butterbach, Katja, Caan, Bette, Casey, Graham, Campbell, Peter T, Chan, Andrew T, Chen, Zhengyi, Chang-Claude, Jenny, Cotterchio, Michelle, Easton, Douglas F, Giles, Graham G, Giovannucci, Edward, Grady, William M, Hoffmeister, Michael, Hopper, John L, Hsu, Li, Jenkins, Mark A, Joshi, Amit D, Lampe, Johanna W, Larsson, Susanna C, Lejbkowicz, Flavio, Li, Li, Lindblom, Annika, Le Marchand, Loic, Martin, Vicente, Milne, Roger L, Moreno, Victor, Newcomb, Polly A, Offitt, Kenneth, Ogino, Shuji, Pharoah, Paul D P, Pinchev, Mila, Potter, John D, Rennert, Hedy S, Rennert, Gad, Saliba, Walid, Schafmayer, Clemens, Schoen, Robert E, Schrotz-King, Petra, Slattery, Martha L, Song, Mingyang, Stegmaier, Christa, Weinstein, Stephanie J, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Gruber, Stephen B, Peters, Ulrike, White, Emily
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Mendelian Randomization
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659358/
https://ncbi.nlm.nih.gov/pubmed/30476131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyy244
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