Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease

OBJECTIVE: Given the known strong relationship of DNA methylation with environmental exposure, we investigated whether brain regions affected in Parkinson disease (PD) were differentially methylated between PD cases and controls. METHODS: DNA chip arrays were used to perform a genome-wide screen of...

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Detalhes bibliográficos
Publicado no:Neurol Genet
Main Authors: Young, Juan I., Sivasankaran, Sathesh K., Wang, Lily, Ali, Aleena, Mehta, Arpit, Davis, David A., Dykxhoorn, Derek M., Petito, Carol K., Beecham, Gary W., Martin, Eden R., Mash, Deborah C., Pericak-Vance, Margaret, Scott, William K., Montine, Thomas J., Vance, Jeffery M.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659138/
https://ncbi.nlm.nih.gov/pubmed/31403079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000342
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