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New family with HSPB8-associated autosomal dominant rimmed vacuolar myopathy

OBJECTIVE: We clinically and molecularly characterize a new family with autosomal dominant rimmed vacuolar myopathy (RVM) caused by mutations in the HSPB8 gene. METHODS: We performed whole-exome and whole-genome sequencing in the family. Western blot and immunocytochemistry were used to analyze 3 pa...

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Detalhes bibliográficos
Publicado no:Neurol Genet
Main Authors: Al-Tahan, Sejad, Weiss, Lan, Yu, Howard, Tang, Sha, Saporta, Mario, Vihola, Anna, Mozaffar, Tahseen, Udd, Bjarne, Kimonis, Virginia
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659134/
https://ncbi.nlm.nih.gov/pubmed/31403083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000349
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