Pharmacological characterization of the seven human NOX isoforms and their inhibitors

BACKGROUND: NADPH oxidases (NOX) are a family of flavoenzymes that catalyze the formation of superoxide anion radical (O(2)(•-)) and/or hydrogen peroxide (H(2)O(2)). As major oxidant generators, NOX are associated with oxidative damage in numerous diseases and represent promising drug targets for se...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Augsburger, Fiona, Filippova, Aleksandra, Rasti, Delphine, Seredenina, Tamara, Lam, Magdalena, Maghzal, Ghassan, Mahiout, Zahia, Jansen-Dürr, Pidder, Knaus, Ulla G., Doroshow, James, Stocker, Roland, Krause, Karl-Heinz, Jaquet, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658998/
https://ncbi.nlm.nih.gov/pubmed/31330481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101272
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