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Sphingosine-1-Phosphate and Macrophage Biology—How the Sphinx Tames the Big Eater

The sphingolipid sphingosine-1-phosphate (S1P) is produced by sphingosine kinases to either signal through intracellular targets or to activate a family of specific G-protein-coupled receptors (S1PR). S1P levels are usually low in peripheral tissues compared to the vasculature, forming a gradient th...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Weigert, Andreas, Olesch, Catherine, Brüne, Bernhard
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658986/
https://ncbi.nlm.nih.gov/pubmed/31379883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01706
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