Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical Carcinoma

Background: Adrenocortical carcinoma (ACC) is a rare tumor entity with restricted therapeutic opportunities. HSP90 (Heat Shock Protein 90) chaperone activity is fundamental for cell survival and contributes to different oncogenic signaling pathways. Indeed, agents targeting HSP90 function have shown...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Siebert, Claudia, Ciato, Denis, Murakami, Masanori, Frei-Stuber, Ludwig, Perez-Rivas, Luis Gustavo, Monteserin-Garcia, José Luis, Nölting, Svenja, Maurer, Julian, Feuchtinger, Annette, Walch, Axel K., Haak, Harm R., Bertherat, Jérôme, Mannelli, Massimo, Fassnacht, Martin, Korpershoek, Esther, Reincke, Martin, Stalla, Günter K., Hantel, Constanze, Beuschlein, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658895/
https://ncbi.nlm.nih.gov/pubmed/31379752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00487
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