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The Complement Receptors C3aR and C5aR Are a New Class of Immune Checkpoint Receptor in Cancer Immunotherapy

Cancer immunotherapy has made remarkable clinical advances in recent years. Antibodies targeting the immune checkpoint receptors PD-1 and CTLA-4 and adoptive cell therapy (ACT) based on ex vivo expanded peripheral CTLs, tumor infiltrating lymphocytes (TILs), gene-engineered TCR- and chimeric antigen...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wang, Yu, Zhang, Hui, He, You-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658873/
https://ncbi.nlm.nih.gov/pubmed/31379815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01574
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