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Histopathologic Correlates of Familial Hemophagocytic Lymphohistiocytosis Isolated to the Central Nervous System

Familial hemophagocytic lymphohistiocytosis (HLH) is an immune hyperactivation syndrome caused by mutations in genes associated with cytotoxic T-cell and NK-cell function. While neurological manifestations frequently accompany systemic inflammation at initial presentation, isolated central nervous s...

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Bibliografske podrobnosti
izdano v:J Neuropathol Exp Neurol
Main Authors: Solomon, Isaac H, Li, Hojun, Benson, Leslie A, Henderson, Lauren A, Degar, Barbara A, Gorman, Mark P, Duncan, Christine N, Lidov, Hart G, Alexandrescu, Sanda
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658858/
https://ncbi.nlm.nih.gov/pubmed/30295794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nly094
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