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The Repurposed Drug Disulfiram Inhibits Urease and Aldehyde Dehydrogenase and Prevents In Vitro Growth of the Oomycete Pythium insidiosum

Pythium insidiosum is an oomycete microorganism that causes a life-threatening infectious disease, called pythiosis, in humans and animals. The disease has been increasingly reported worldwide. Conventional antifungal drugs are ineffective against P. insidiosum. Treatment of pythiosis requires the e...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Krajaejun, Theerapong, Lohnoo, Tassanee, Yingyong, Wanta, Rujirawat, Thidarat, Kumsang, Yothin, Jongkhajornpong, Passara, Theerawatanasirikul, Sirin, Kittichotirat, Weerayuth, Reamtong, Onrapak, Yolanda, Hanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658754/
https://ncbi.nlm.nih.gov/pubmed/31138572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00609-19
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