Evaluation of the Synergy of Ceftazidime-Avibactam in Combination with Meropenem, Amikacin, Aztreonam, Colistin, or Fosfomycin against Well-Characterized Multidrug-Resistant Klebsiella pneumoniae and Pseudomonas aeruginosa

Multidrug-resistant (MDR) Gram-negative organisms are a major health concern due to lack of effective therapy. Emergence of resistance to newer agents like ceftazidime-avibactam (CZA) further magnifies the problem. In this context, combination therapy of CZA with other antimicrobials may have potent...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Mikhail, Sandra, Singh, Nivedita B., Kebriaei, Razieh, Rice, Seth A., Stamper, Kyle C., Castanheira, Mariana, Rybak, Michael J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658738/
https://ncbi.nlm.nih.gov/pubmed/31182535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00779-19
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