Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model

Transplantation of cardiomyocytes derived from induced pluripotent stem cell (iPSC-CMs) is a promising approach for increasing functional CMs during end-stage heart failure. Although major histocompatibility complex (MHC) class I matching between donor cells and recipient could reduce acquired immun...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakamura, Yuki, Miyagawa, Shigeru, Yoshida, Shohei, Sasawatari, Shigemi, Toyofuku, Toshihiko, Toda, Koichi, Sawa, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658523/
https://ncbi.nlm.nih.gov/pubmed/31346220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47134-3
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