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Intracellular compartment-specific proteasome dysfunction in postmortem cortex in schizophrenia subjects

Protein homeostasis is an emerging component of schizophrenia (SZ) pathophysiology. Proteomic alterations in SZ are well-documented and changes in transcript expression are frequently not associated with changes in protein expression in SZ brain. The underlying mechanism driving these changes remain...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Scott, Madeline R., Meador-Woodruff, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658356/
https://ncbi.nlm.nih.gov/pubmed/30683941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0359-7
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