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NFκB activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of nephrogenic systemic fibrosis

OBJECTIVE: Nephrogenic systemic fibrosis (NSF) is a generalised fibrotic disorder occurring in certain individuals with renal insufficiency exposed to gadolinium-based contrast agents (GdBCA) for MRI. Histopathological examination of affected tissues shows increased numbers of activated macrophages....

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Del Galdo, Francesco, Wermuth, Peter J, Addya, Sankar, Fortina, Paolo, Jimenez, Sergio A
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658210/
https://ncbi.nlm.nih.gov/pubmed/20959327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2010.134858
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