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Maternal Uniparental Disomy 14 (UPD14) Identified by Clinical Exome Sequencing in an Adolescent with Diverticulosis

Pediatric diverticular disease is extremely rare, with most cases associated with connective tissue disorders. We report an adolescent boy with syndromic features who presented with acute complicated sigmoid diverticulitis. Clinical exome sequencing analysis detected a 6.5-Mb region of homozygosity...

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Bibliographische Detailangaben
Veröffentlicht in:ACG Case Rep J
Hauptverfasser: Chan, Alvin P., Mulatinho, Milene, Iskander, Paul, Lee, Hane, Martinez-Agosto, Julian A., Yeh, Joanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658016/
https://ncbi.nlm.nih.gov/pubmed/31620490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14309/crj.0000000000000021
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