Inflammatory monocytes provide a niche for Salmonella expansion in the lumen of the inflamed intestine

Salmonella exploit host-derived nitrate for growth in the lumen of the inflamed intestine. The generation of host-derived nitrate is dependent on Nos2, which encodes inducible nitric oxide synthase (iNOS), an enzyme that catalyzes nitric oxide (NO) production. However, the cellular sources of iNOS a...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: McLaughlin, Patrick A., Bettke, Julie A., Tam, Jason W., Leeds, Jesse, Bliska, James B., Butler, Brian P., van der Velden, Adrianus W. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658010/
https://ncbi.nlm.nih.gov/pubmed/31306468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007847
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