Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway

Lung cancer is one of the leading causes of cancer-associated mortality in China and globally. Gemcitabine (GEM), as a first-line therapeutic drug, has been used to treat lung cancer, but GEM resistance poses a major limitation on the efficacy of GEM chemotherapy. Alantolactone (ALT), a sesquiterpen...

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Publicado en:Int J Mol Med
Autores principales: Wang, Jiquan, Zhang, Yingbing, Liu, Xu, Wang, Jizhao, Li, Bin, Liu, Yongkang, Wang, Jiansheng
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2019
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657978/
https://ncbi.nlm.nih.gov/pubmed/31524219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4268
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