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Aneuploidy Enables Cross-Adaptation to Unrelated Drugs

Aneuploidy is common both in tumor cells responding to chemotherapeutic agents and in fungal cells adapting to antifungal drugs. Because aneuploidy simultaneously affects many genes, it has the potential to confer multiple phenotypes to the same cells. Here, we analyzed the mechanisms by which Candi...

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Dettagli Bibliografici
Pubblicato in:Mol Biol Evol
Autori principali: Yang, Feng, Teoh, Flora, Tan, Alrina Shin Min, Cao, Yongbing, Pavelka, Norman, Berman, Judith
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657732/
https://ncbi.nlm.nih.gov/pubmed/31028698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz104
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