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Manipulating Immune Activation of Macrophages by Tuning the Oligonucleotide Composition of Gold Nanoparticles

This paper describes how the ligand shell containing immunostimulatory oligonucleotides surrounding gold nanoparticles affects the in vitro activation of macrophages. Nanoconstructs with similar ligand densities but different oligonucleotide compositions (from 0 to 100% immune-active cytosine-phosph...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Pallares, Roger M., Choo, Priscilla, Cole, Lisa E., Mirkin, Chad A., Lee, Andrew, Odom, Teri W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657697/
https://ncbi.nlm.nih.gov/pubmed/31243978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.9b00316
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