Llwytho...
Affinity of fentanyl and its derivatives for the σ(1)-receptor
Fentanyl and its 11 commercially available derivatives were investigated as to their affinity for the σ(1) receptor. The parent compound is a rather poor binder (IC(50) = 4973 nM), but its close derivatives (benzylfentanyl or p-fluorofentanyl) have submicromolar affinities. Modelling provides a stru...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Medchemcomm |
|---|---|
| Prif Awduron: | , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Royal Society of Chemistry
2019
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6657672/ https://ncbi.nlm.nih.gov/pubmed/31391893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00222g |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|