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Mixed Vehicle Emissions Induces Angiotensin II and Cerebral Microvascular Angiotensin Receptor Expression in C57Bl/6 Mice and Promotes Alterations in Integrity in a Blood-Brain Barrier Coculture Model

Exposure to traffic-generated pollution is associated with alterations in blood-brain barrier (BBB) integrity and exacerbation of cerebrovascular disorders. Angiotensin (Ang) II signaling through the Ang II type 1 (AT(1)) receptor is known to promote BBB disruption. We have previously reported that...

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Bibliographic Details
Published in:Toxicol Sci
Main Authors: Suwannasual, Usa, Lucero, JoAnn, Davis, Griffith, McDonald, Jacob D, Lund, Amie K
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657584/
https://ncbi.nlm.nih.gov/pubmed/31132127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz121
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