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Presymptomatic Treatment With Andrographolide Improves Brain Metabolic Markers and Cognitive Behavior in a Model of Early-Onset Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common type of dementia. The onset and progression of this pathology are correlated with several changes in the brain, including the formation of extracellular aggregates of amyloid-beta (Aβ) peptide and the intracellular accumulation of hyperphosphorylated tau p...

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Publicat a:Front Cell Neurosci
Autors principals: Cisternas, Pedro, Oliva, Carolina A., Torres, Viviana I., Barrera, Daniela P., Inestrosa, Nibaldo C.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657419/
https://ncbi.nlm.nih.gov/pubmed/31379502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00295
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