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Mitochondrial Reactive Oxygen Species Generated at the Complex-II Matrix or Intermembrane Space Microdomain Have Distinct Effects on Redox Signaling and Stress Sensitivity in Caenorhabditis elegans

Aims: How mitochondrial reactive oxygen species (ROS) impact physiological function may depend on the quantity of ROS generated or removed, and the subcellular microdomain in which this occurs. However, pharmacological tools currently available to alter ROS production in vivo lack precise spatial an...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Trewin, Adam J., Bahr, Laura L., Almast, Anmol, Berry, Brandon J., Wei, Alicia Y., Foster, Thomas H., Wojtovich, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657295/
https://ncbi.nlm.nih.gov/pubmed/30887829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2018.7681
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