KIFC1 is activated by TCF-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity

BACKGROUND: Kinesins play important roles in the development and progression of many human cancers. The functions and underlying mechanisms of kinesin family member C1 (KIFC1), a member of the kinesin-14 family, in the pathogenesis of hepatocellular carcinoma (HCC) have not been fully elucidated. ME...

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Bibliografiske detaljer
Udgivet i:	J Exp Clin Cancer Res
Main Authors:	Teng, Kai, Wei, Shi, Zhang, Chi, Chen, Jiewei, Chen, Jinbin, Xiao, Kanghua, Liu, Jun, Dai, Miaomiao, Guan, Xinyuan, Yun, Jingping, Xie, Dan
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2019
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6657086/ https://ncbi.nlm.nih.gov/pubmed/31340839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1331-8
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KIFC1 is activated by TCF-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity

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