Patterns of failure after immunotherapy with checkpoint inhibitors predict durable progression-free survival after local therapy for metastatic melanoma

BACKGROUND: Checkpoint inhibitors (CPI) have revolutionized the treatment of metastatic melanoma, but most patients treated with CPI eventually develop progressive disease. Local therapy including surgery, ablation or stereotactic body radiotherapy (SBRT) may be useful to manage limited progression,...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Klemen, Nicholas D., Wang, Melinda, Feingold, Paul L., Cooper, Kirsten, Pavri, Sabrina N., Han, Dale, Detterbeck, Frank C., Boffa, Daniel J., Khan, Sajid A., Olino, Kelly, Clune, James, Ariyan, Stephan, Salem, Ronald R., Weiss, Sarah A., Kluger, Harriet M., Sznol, Mario, Cha, Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657062/
https://ncbi.nlm.nih.gov/pubmed/31340861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0672-3
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