Epigenome-wide association study of asthma and wheeze characterizes loci within HK1

BACKGROUND: To identify novel epigenetic markers of adolescent asthma and replicate findings in an independent cohort, then explore whether such markers are detectable at birth, predictive of early-life wheeze, and associated with gene expression in cord blood. METHODS: We performed epigenome-wide s...

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Vydáno v:Allergy Asthma Clin Immunol
Hlavní autoři: Everson, Todd M., Zhang, Hongmei, Lockett, Gabrielle A., Kaushal, Akhilesh, Forthofer, Melinda, Ewart, Susan L., Burrows, Kimberley, Relton, Caroline L., Sharp, Gemma C., Henderson, A. John, Patil, Veeresh K., Rezwan, Faisal I., Arshad, S. Hasan, Holloway, John W., Karmaus, Wilfried
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657035/
https://ncbi.nlm.nih.gov/pubmed/31367216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13223-019-0356-z
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