Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7

Iodide transport and storage in the thyroid follicles is crucial for thyroid hormone synthesis. Pendrin, the iodide exporter that transports iodide to thyroid follicles, is responsible for Pendred syndrome, a disorder characterized by congenital hypothyroidism and hearing loss. However, thyroid horm...

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Bibliografiske detaljer
Udgivet i:Commun Biol
Main Authors: Ishii, Jun, Suzuki, Atsushi, Kimura, Toru, Tateyama, Michihiro, Tanaka, Tatsushi, Yazawa, Takuya, Arimasu, Yu, Chen, I-Shan, Aoyama, Kohei, Kubo, Yoshihiro, Saitoh, Shinji, Mizuno, Haruo, Kamma, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656751/
https://ncbi.nlm.nih.gov/pubmed/31372509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0503-6
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