High IDO1 Expression Is Associated with Poor Outcome in Patients with Anal Cancer Treated with Definitive Chemoradiotherapy

BACKGROUND. This study characterizes the tumor‐immune microenvironment in pretreatment, localized anal squamous cell carcinoma (ASCC), including two markers that have not previously been studied in ASCC: indoleamine 2,3 dioxygenase 1 (IDO1) and human leukocyte antigen (HLA) class I. MATERIALS AND ME...

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Veröffentlicht in:Oncologist
Hauptverfasser: Mitra, Devarati, Horick, Nora K., Brackett, Diane G., Mouw, Kent W., Hornick, Jason L., Ferrone, Soldano, Hong, Theodore S., Mamon, Harvey, Clark, Jeffrey W., Parikh, Aparna R., Allen, Jill N., Ryan, David P., Ting, David T., Deshpande, Vikram, Wo, Jennifer Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2019
Schlagworte:
Gastrointestinal Cancer
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656510/
https://ncbi.nlm.nih.gov/pubmed/30755500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0794
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