High IDO1 Expression Is Associated with Poor Outcome in Patients with Anal Cancer Treated with Definitive Chemoradiotherapy

BACKGROUND. This study characterizes the tumor‐immune microenvironment in pretreatment, localized anal squamous cell carcinoma (ASCC), including two markers that have not previously been studied in ASCC: indoleamine 2,3 dioxygenase 1 (IDO1) and human leukocyte antigen (HLA) class I. MATERIALS AND ME...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Mitra, Devarati, Horick, Nora K., Brackett, Diane G., Mouw, Kent W., Hornick, Jason L., Ferrone, Soldano, Hong, Theodore S., Mamon, Harvey, Clark, Jeffrey W., Parikh, Aparna R., Allen, Jill N., Ryan, David P., Ting, David T., Deshpande, Vikram, Wo, Jennifer Y.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Gastrointestinal Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656510/
https://ncbi.nlm.nih.gov/pubmed/30755500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0794
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